Jhonen Vasquez
- Birthday: 1974-09-01
- Place of birth: San Jose, California, USA
Jhonen C. Vasquez is an American comic book writer, cartoonist, and music video director. He is best known for creating the comic book Johnny the Homicidal Maniac, its spin-off comics Squee! and I Feel Sick, and the Nickelodeon animated series Invader Zim.
